The MOUSE ANTI HUMAN BRAIN NATRIURETIC PEPTIDE Antibody from MyBioSource.com is a Mouse Monoclonal antibody to BNP, Brain Natriuretic Peptide, and NPPB. This antibody recognizes Human antigen. The MOUSE ANTI HUMAN BRAIN NATRIURETIC PEPTIDE Antibody has been validated for the following applications: Immunoassay, ELISA, and Western Blot.
Description
Mouse anti Human Brain Natriuretic Peptide antibody, clone 50E1 detects an epitope located at the C-terminal (amino acids 26-32) of the human brain natriuretic peptide (BNP), a secreted protein which is a member of the natriuretic peptide family. BNP is a cardiac hormone, which is synthesised as a pro-hormone (proBNP), and is proteolytically cleaved to release a biologically active fragment (BNP), and an inactive fragment (NT-proBNP) into the circulation. BNP is predominantly secreted from the cardiac ventricles in response to volume and pressure overload, and results in a number of biological activities including natriuresis, diuresis, vasorelaxation, and inhibition of the sympathetic nervous system. A high concentration of BNP in the bloodstream is indicative of heart failure. Mouse anti Human Brain Natriuretic Peptide antibody, clone 50E1 also detects proBNP